The degree of activation of the immune system during atezolizumab therapy measured by the level of selected soluble proteins in blood serum
Project implementation: 7/11/2019 - 6/11/2020
Project manager: dr Anna Siemiątkowska
Development of the HPLC-MS/MS method for the determination of ticagrelor and its metabolite
Project implementation: 01/10/2017 - 30/09/2018
Project manager: dr Dorota Danielak
Assessment of the impact of the interaction between clopidogrel and statins with different pharmacokinetic properties on the therapeutic effect of clopidogrel in patients undergoing angiography/coronary angioplasty
Project implementation: 11/08/2015 - 10/08/2019
Project manager: dr Marta Karaźniewicz-Łada
Pharmacokinetics and organ distribution of treosulfan and its biologically active epoxytransformer in rats
Project implementation: 28/01/2015 - 27/08/2018
Project manager: dr Michał Romański
11β-hydroxysteroid dehydrogenase 2 activity in pregnant women with hypertension
Project implementation: 12/03/2013 - 11/09/2017
Project manager: prof. dr hab. Franciszek Główka
Assessment of pharmacogenetic risk factors for clopidogrel resistance in patients with type 2 diabetes
Project implementation: 26/10/2010-25/10/2013
Project manager: dr Marta Karaanniewicz-Łada
Analysis of endogenous levels of glucocorticoids and their metabolites as a diagnostic criteria for metabolic disorders in humans including the assessment of the genetic polymorphism of the 11β-hydroxysteroid dehydrogenase enzyme isoform 2
Project implementation: 17/09/2007-16/09/2010
Project manager: prof. UM dr hab. Franciszek Główka
Preparation, structure, selected physicochemical and biological properties of some salts of the product and photodegradation of papaverine
Cooperation with the Christian University of Albrecht in Kiel
Project implementation: 24/09/08-31/03/2010
Project manager: prof. dr hab. Tadeusz Hermann
Pharmaceutical and biological availability of gliclazide from immediate-release (IR) and slow-release (SR) tablets
Project implementation: 16/05/2008 - 30/11/2009
Project manager: prof. dr hab. Tadeusz Hermann
Genetic polymorphism of thiopurine methyltransferase (TPMT) and its clinical significance in the treatment of acute lymphocytic leukemia (ALL) in children
Project implementation: 10/5/2005-06/11/2006
Project manager: dr hab. Maria Chrzanowska
HPCE method for the determination of enantiomers of 2-arylpropionic acid derivatives and their metabolites in biological fluids for pharmacokinetic studies, including CYP2C9 and CYP2C8 isoenzymes
Project manager: dr hab. Franciszek Główka
Project implementation: 2006
Drug form and pharmacokinetics of enantiomers of 2-arylpropionic and 2-aryl butanic acid derivatives with different degree of ionization
Subject supervisor: dr hab. Franciszek Główka prof. UM
Project implementation: 1998-2000
Evaluation of the pharmaceutical preparation of clopidogrel for use in patients with cardiovascular disorders
Project manager: dr hab. Franciszek Główka prof. UM
Modification of the HPLC-UV method for the determination of mono- and diepoxide activation product of treosulfan in aqueous solution and plasma
Project manager: dr hab. Franciszek Główka prof. UM
Project implementation: 2009
Genetic polymorphism of thiopurine methyltransferase (TPMT) and its clinical significance in the treatment of acute myeloid leukemia (AML) in children
Project manager: dr hab. Maria Chrzanowska prof. UM
Implementation of the project: 2008
Pharmacokinetics of treosulfan in patients undergoing myeloablative therapy
Project manager: dr hab. Franciszek Główka prof. UM
Project implementation: 2008
Synthesis of 6a,12a-diazadibenzo-[a,g]-flueroneryl derivatives with the use of oxide and metal catalysts
Project manager: prof. dr hab. Tadeusz Hermann
Project implementation: 2008
Preparation of a brown decomposition product of papaverine hydrochloride and its derivatives
Project manager: prof. dr hab. Tadeusz Hermann
Project implementation: 2006
Development of the HPLC method (HPCE) of endogenous steroids and their metabolites
Project manager: dr hab. Franciszek Główka
Project implementation: 2006
Analysis of thiopurine methyltransferase (TPMT) genotype in children with acute myeloid leukemia
Project manager: dr hab. Maria Chrzanowska prof. UM
Project implementation: 2006
Assessment of kinetic parameters of treosulfan activation and hydrolysis of its biologically active epoxy derivatives as an indicator in predicting their levels in children conditioned before hematopoietic cell transplantation
Project supervisor: dr hab. Franciszek Główka prof. UM
Project implementation: 2010