Clinical pharmacokinetics

Clinical Pharmacokinetics

Year of studies: 5th PharmD Program

Type of course: Mandatory

Course coordinator: prof. Franciszek Główka

Lectures: 10 hours – prof. Franciszek Główka

Practical classes: 20 hours – prof. dr hab. Franciszek Główka, dr hab. Marta Karaźniewicz-Łada,               dr Katarzyna Kosicka

Preliminary requirements:

pharmacokinetics, pharmacology

Course objectives:

An advanced course that combines the theoretical and case-based information concerning Therapeutic Drug Monitoring. The course will prepare students to manage with dosing regimens of drugs with a narrow therapeutic index and to concern the specific kinetic properties of the active compounds in dosing determination. The course will prepare pharmacists as a potential specialist evaluating dosing regimens for individual patients, based on pharmacokinetic calculations. The expert knowledge of pharmacist about the determinants of safe therapy for the patients will ensure that the pharmacists will be important and desirable partners of the clinical team of modern pharmacotherapy.

Course content:

The course will take place at the Department of Physical Pharmacy and Pharmacokinetics (Coll. Anatomicum, 6 Święcickiego Str.).


1. Immunosuppressives (lecture and practice)

2. Antibiotics (lecture and practice)

3. Antiarrhythmics (lecture and practice) - 1 and 2

4. Antiepileptics (lecture and practice)
     pract.: Antiepileptics
(Description and Report)

5. Antifungals (lecture and practice)

 Form of final assessment: Test


Primary literature
  1. Bauer LA Applied clinical pharmacokinetics , McGraw-Hill, 2008.
  2. Shargel L, Wu-Pong S Applied biopharmaceutics & pharmacokinetics , McGraw-Hill, 2005.
  3. Burton ME, Shaw LM, Schentag JJ, Williams WE Applied pharmacokinetics & pharmacodynamics , Lippincott Williams & Wilkins, 2006.
Complementary literature
  1. Tozer TN, Rowland M Introduction to pharmacokinetics and pharmacodynamics. The quantitative basis of drug therapy , Lippincott Wiliams & Wilkins, 2006.